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  • An article published on The American Journal on Addictions stated that expecting mothers who were enslaved by opioids were strongly considering antagonist treatment, especially the one which involves the using naltrexone to combat their abusing drugs disorder.

    Using two separate drugs to shed pounds can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people that go through it you need to err to the side of caution and allow the FDA do its job and demand some investigation be done so the public is aware of the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to generate income and that they would say anything to keep people on his or her medications.

    Researchers found that participants investing in this drug for the year, lost weight within 4 weeks and have kept the weight off through the entire 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, which can make them more effective and safer.

    Combo-pilling will be the newest fad or also the newest in the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular may be the fact that since right now there are not any long term prescription weight loss supplements that have been authorized by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA.

    Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise hypertension and heartbeat, and really should not be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure and pulse rate and must 't be used in patients with uncontrolled high blood pressure level, and also by a person with heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients with a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

    "There were no warning signs of depression or suicidal thoughts in trial participants," said Fujioka.