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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment selection for chronic weight reduction in addition to a reduced-calorie diet and exercise.
Using two separate drugs to lose weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it one should err to the side of caution and allow the FDA do its job and demand some investigation be done in order that the public understands the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies have been in business to make money and that they would say almost anything to keep people on their medications.
Researchers found that participants using this drug for a year, lost excess weight within four weeks and have kept the load off throughout the 56 weeks with the study. Contrave is really a combination from the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of multiple active ingredient, which might make them more efficient and safer.
Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and thus it is just more publicly known lately, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular is the fact that since right now there are no long term prescription diet pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be approved by the FDA.
Seizures really are a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug also can raise blood pressure and pulse rate, and must not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise hypertension and pulse rate and must stop used in patients with uncontrolled high blood pressure, and also by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert physicians and patients to the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.
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