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Evidence is increasing that most addiction without exception is related to issues with the brain's reward center, particularly the mesolimbic system. This section of the problem regulates reward responses in getting food and sex, along with nurturing infants and children. One of the most important neurotransmitters linked to reward responses, both when they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the level of dopamine released in responding to a stimulus"(Bostwick & Bucci, 2008).
Using two separate drugs to lose weight naturally can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err on the side of caution and permit the FDA do its job and demand some research be done so your public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies come in business to generate money and that they would say almost anything to keep people on their medications.
Researchers found out that participants taking this drug to get a year, lost weight within four weeks and have kept the body weight off throughout the 56 weeks in the study. Contrave is often a combination from the drugs naltrexone and bupropion, which seems to reflect a whole new trend of weight-loss drugs that are made up of more than one active ingredient, which can make them more efficient and safer.
Combo-pilling is the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is now popular is the fact that by right now there aren't long term prescription diet pills that have been approved by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.
Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug can also raise blood pressure and heartbeat, and really should not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise blood pressure and heartrate and must not used in patients with uncontrolled high hypertension, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients for the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.
From a psychiatric viewpoint, evidence suggests that the ordinary neural mechanism for goal-directed behavior may be hijacked by the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus along with the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).