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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight loss in addition to a reduced-calorie diet and exercising.
Using two separate drugs to shed weight can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you should err to the side of caution and allow the FDA do its job and demand some investigation be done in order that the public understands the side effects and hazards of the medications before we take them. Keep in mind that drug companies are in business to generate money and that they would say almost anything to keep people on their medications.
Researchers found that participants investing in this drug to get a year, dropped a few pounds within four weeks and have kept the weight off during the entire 56 weeks from the study. Contrave is often a combination in the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them more effective and safer.
Combo-pilling will be the newest fad or also the newest in the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular may be the fact that since right now there aren't long term prescription slimming capsules that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be licensed by the FDA.
Seizures are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug can also raise blood pressure level and heartrate, and shouldn't be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise hypertension and heartrate and must stop used in patients with uncontrolled high hypertension, along with by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients which has a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking.
Most of the combinations which can be used to enhance weight loss involve an amphetamine as well as an antidepressant. Phentermine and Prozac certainly are a popular combination which were around for a long time, and although it has been around nobody wants to truly combine both the and try to get FDA approval to showcase it as a fat loss pill. Right there should raise some red flags if the greedy pharmaceutical companies should not be involved in combining medications and selling them something should be wrong using the combination. In fairness there is one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, used to treat alcohol and substance abuse, using the antidepressant bupropion (Wellbutrin, Zyban) it has been given the go ahead to move forward by an FDA advisory committee, but at the time of yet will not be approved.