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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment option for chronic weight reduction in addition to a reduced-calorie diet and exercise.
Using two separate drugs to shed weight can be very effective you'll find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err on the side of caution and let the FDA do its job and demand some research be done so the public understands the side effects and risks of the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say everything to keep people on their medications.
Researchers found that participants investing in this drug for any year, lost weight within four weeks and have kept the body weight off during the entire 56 weeks of the study. Contrave is often a combination in the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which can make them far better and safer.
Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular could be the fact that as of right now there aren't any long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA.
Seizures can be a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug could also raise blood pressure level and heartbeat, and shouldn't be used in people with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.
The FDA also warned that Contrave can raise blood pressure and heart rate and must stop used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical researchers and patients on the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.
From a psychiatric standpoint, evidence shows that the ordinary neural mechanism for goal-directed behavior has been hijacked through the addiction, and malfunctions in such a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus as well as the person engages in a "goal-directed behavioral response" that generates a "natural high"(Bostwick & Bucci, 2008).