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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight reduction in addition to a reduced-calorie diet and physical activity.
Using two separate drugs to shed pounds can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it one should err on the side of caution and let the FDA do its job and demand some investigation be done in order that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on their own medications.
Researchers discovered that participants using this drug for any year, lost weight within four weeks and have kept the extra weight off throughout the 56 weeks in the study. Contrave is a combination from the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs which might be made up of more than one active ingredient, which might make them far better and safer.
Combo-pilling will be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular could be the fact that as of right now there are not any long term prescription diet pills that have been licensed by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be authorized by the FDA.
Seizures really are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and heart rate, and mustn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise blood pressure levels and heartrate and must stop used in patients with uncontrolled high blood pressure, as well as by you aren't heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients on the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.
The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.