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On September 26, UCLA researcher reported the final results of a study, which indicated that Asians who will be struggling with alcoholism will benefit especially from naltrexone, among three medications approved by the U.S. Food and Drug Administration (FDA) for the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that makes them likely to benefit from naltrexone, weighed against about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are still available online ( within the journal Neuropsychopharmacology and will also be published in a upcoming print edition from the journal.
Using two separate drugs to shed weight can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people who go through it you should err along the side of caution and let the FDA do its job and demand some investigation be done in order that the public understands the side effects and risks of the medications before we bring them. Keep in mind that drug companies have been in business to earn money and that they would say anything to keep people on the medications.
Researchers discovered that participants investing in this drug to get a year, lost excess weight within a month and have kept the extra weight off through the entire 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a brand new trend of weight-loss drugs which can be made up of many active ingredient, which may make them more efficient and safer.
Combo-pilling will be the newest fad or also the newest to come under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular will be the fact that by right now there are no long term prescription weight loss supplements that have been licensed by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations have been rejected or have yet to be licensed by the FDA.
Seizures really are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise blood pressure level and heart rate, and shouldn't be used in individuals with a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure and heartrate and must not be used in patients with uncontrolled high blood pressure, in addition to by a person with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.
Most of the combinations that are used to enhance weight loss involve an amphetamine and an antidepressant. Phentermine and Prozac can be a popular combination which were around for quite a while, and even though it has been around stuffed to truly combine both the and try to get FDA approval to advertise it as a weight-loss pill. Right there should raise some warning signs if the greedy pharmaceutical companies do not want to be involved in combining medications and selling them something must be wrong with the combination. In fairness there is certainly one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, used to treat alcohol and abusing drugs, while using antidepressant bupropion (Wellbutrin, Zyban) it's been given the proceed to move forward by an FDA advisory committee, but as of yet hasn't been approved.