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On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who will be struggling with alcoholism may benefit especially from naltrexone, certainly one of three medications approved by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent possess a particular mutation that makes them likely to benefit from naltrexone, in comparison with about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are available online ( inside the journal Neuropsychopharmacology and will be published within an upcoming print edition with the journal.
Using two separate drugs to shed pounds can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it you need to err assisting caution and permit the FDA do its job and demand some research be done so your public recognizes the side effects and hazards of the medications before we bring them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications.
Researchers found that participants investing in this drug for any year, lost excess weight within 4 weeks and have kept the weight off during the entire 56 weeks with the study. Contrave is really a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of multiple active ingredient, which might make them more potent and safer.
Combo-pilling will be the newest fad or better yet the newest to come under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular may be the fact that since right now there aren't long term prescription weightloss pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations are actually rejected or have yet to be approved by the FDA.
Seizures are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug may also raise blood pressure and pulse rate, and shouldn't be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.
The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not used in patients with uncontrolled high blood pressure, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting the brain) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients to the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.
From a psychiatric standpoint, evidence points too the ordinary neural mechanism for goal-directed behavior has been hijacked with the addiction, and malfunctions in a way that its ordinary functions are exaggerated and fixated on its object. An object generates a stimulus and also the person engages in a "goal-directed behavioral response" that produces a "natural high"(Bostwick & Bucci, 2008).