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  • It was found that naltrexone and bupropion combined, that could be marketed down the road as Contrave, have better weight loss results than eating and working out alone.

    Using two separate drugs to lose weight naturally can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people who go through it you should err to the side of caution and allow the FDA do its job and demand some investigation be done so that the public understands the side effects and dangers of the medications before we take them. Keep in mind that drug companies come in business to earn money and that they would say everything to keep people on the medications.

    Researchers found that participants taking this drug for the year, dropped a few pounds within four weeks and have kept the load off throughout the 56 weeks of the study. Contrave is often a combination from the drugs naltrexone and bupropion, which seems to reflect a fresh trend of weight-loss drugs that are made up of more than one active ingredient, which might make them far better and safer.

    Combo-pilling will be the newest fad or also the newest into the future under scrutiny and thus it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular could be the fact that by right now there aren't long term prescription diet pills that have been licensed by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA.

    Seizures certainly are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug could also raise blood pressure and heart rate, and shouldn't be used in people who have a history of heart attack or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure level and heart rate and must stop used in patients with uncontrolled high blood pressure level, along with by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting mental performance) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients to the increased likelihood of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for quitting smoking.

    Approving a drug using this many potentially lethal side effects is inconsistent with the mission statement with the FDA. The power with the drug manufacturing lobby is blatantly evident inside approval of numerous drugs requiring 'post-marketing' studies which can be clearly significant to overall drug safety in the US.